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Asthma Diagnose und Therapie

Evidenzbasierte Leitlinie zu Diagnose und Therapie.
Entwickelt durch das medizinische Wissensnetzwerk “evidence.de” der Universität Witten/Herdecke

Version 01/2004

Referenzen


1.Controlled trial of the effects of cortisone acetate in status asthmaticus. Report to the Medical Research Council by the sub committee on clinical trials in. Lancet, 1956. 2: p. 803-6.
Evidenzklasse: IIa
Link:


2.Accuracy of death certificates in bronchial asthma. Accuracy of certification procedures during the confidential inquiry by the British Thoracic Association. A subcommittee of the BTA Research Committee. Thorax, 1984. 39(7): p. 505-9.
Evidenzklasse: III
Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=6463930


3.International consensus report on diagnosis and treatment of asthma. National Heart, Lung, and Blood Institute, National Institutes of Health. Bethesda, Maryland 20892. Publication no. 92-3091, March 1992. Eur Respir J, 1992. 5(5): p. 601-41.
Evidenzklasse: Link:


4.Why mothers die 1997-1999. the fifth report of the confidential enquiries into maternal deaths in the United Kingdom 1997-1999, ed. G. Lewis. 2001, London: RCOG Press.
Evidenzklasse: III
Link:


5.AAAAI and Allergy, Committee on, Practice parameters for the diagnosis and treatment of asthma. Joint Task Force on Practice Parameters, representing the American Academy of Allergy Asthma and Immunology, the American College of Allergy, Asthma and Immunology, and the Joint Council of Allergy, Asthma and Immunology. J Allergy Clin Immunol, 1995. 96(5 Pt 2): p. 707-870.
Evidenzklasse: nicht bewertet
Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=7494078


6.Abdulwadud, O., et al., Attendance at an asthma educational intervention: characteristics of participants and non-participants. Respir Med, 1997. 91(9): p. 524-9.
Evidenzklasse: Ib
Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9415352


7.Aberg, N. and Engstrom, I., Natural history of allergic diseases in children. Acta Paediatr Scand, 1990. 79(2): p. 206-11.
Evidenzklasse: III
Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2321483


8.Abramson, M. J., et al., Are asthma medications and management related to deaths from asthma? Am J Respir Crit Care Med, 2001. 163(1): p. 12-8.
Evidenzklasse: III
Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11208619


9.Abramson, M., Puy, R., and Weiner, J., Immunotherapy in asthma: an updated systematic review. Allergy, 1999. 54(10): p. 1022-41.
Evidenzklasse: Ia
Link:


10.Abramson, MJ, Puy, RM, and Weiner, JM, Allergen immunotherapy for asthma (Cochrane review). Th Cochrane Library, 2001(3).
Evidenzklasse: Ia
Link:


11.Abulhosn, R. S., et al., Passive smoke exposure impairs recovery after hospitalization for acute asthma. Arch Pediatr Adolesc Med, 1997. 151(2): p. 135-9.
Evidenzklasse: III
Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9041867


12.ACOG and ACAAI, The use of newer asthma and allergy medications during pregnancy. The American College of Obstetricians and Gynecologists (ACOG) and The American College of Allergy, Asthma and Immunology (ACAAI). Ann Allergy Asthma Immunol, 2000. 84(5): p. 475-80.
Evidenzklasse: IV
Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10830999


13.Adams, N., Bestall, J., and Jones, P., Inhaled beclomethasone at different doses for long-term asthma. Cochrane Database Syst Rev, 2003. 2.
Evidenzklasse: Ia
Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11279769

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14.Adams, N., Bestall, J., and Jones, P., Inhaled beclomethasone versus placebo for chronic asthma (Cochrane Review). Cochrane Library, 2003(2).
Evidenzklasse: Ia
Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11279769


15.Adams, N., Bestall, J., and Jones, P. W., Inhaled fluticasone proprionate for chronic asthma. Cochrane Database Syst Rev, 2003. 2.
Evidenzklasse: Ia
Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11687040


16.Adams, N., Cates, C., and Bestall, J., Holding chambers versus nebulisers for inhaled steroids in chronic asthma. (Cochrane Review). The Cochrane Library, 2003(2).
Evidenzklasse: Ia
Link:


17.Adams, RJ., Smith, B., and Ruffin, RE., Impact of the physician`s participatory style in asthma outcomes and patient satisfaction. Ann Allergy Asthma Immunol, 2001. 86: p. 263-71.
Evidenzklasse: Link:


18.AEZQ and Qualitätssicherung, Ärztliche Zentralstelle, Stellungnahme zur Anfrage
des Sachverständigenrates für die Konzertierte Aktion im Gesundheitswesen. 2000.
Evidenzklasse: IV
Link:
http://www.svr-gesundheit.de/befragung/id-nummern/018.pdf


19.Agertoft, L. and Pedersen, S., Effects of long-term treatment with an inhaled corticosteroid on growth and pulmonary function in asthmatic children. Respir Med, 1994. 88(5): p. 373-81.
Evidenzklasse: IIa
Link:


20.AHCPR, Merkel, S. L., and Van Meter, M. J., AHCPR guideline: pain management. Ohio Nurses Rev, 1993. 68(2): p. 12.
Evidenzklasse: nicht bewertet
Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8469514


21.AKDAE and Ärzteschaft, Arzneimittelkommission der dt., Empfehlungen zur Therapie des
Asthma bronchiale im Erwachsenenalter. AVP-Sonderheft Therapieempfehlungen, 1. Auflage, September 2001, 2001.
Evidenzklasse: Link:


22.Alcock, S. M., et al., Symptoms and pulmonary function in asthma. Respir Med, 1998. 92(6): p. 849-57.
Evidenzklasse: IV
Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9850369


23.Allen, R. M., Jones, M. P., and Oldenburg, B., Randomised trial of an asthma self-management programme for adults. Thorax, 1995. 50(7): p. 731-8.
Evidenzklasse: Ib
Link:


24.Anastasatu, C., Dutu, S., and Morgenstern, H., Possibilities of reducing the efficient dose of fenotherol by combining it with ipratropiumbromide in bronchial asthma. Prax Klin Pneumol, 1983. 37 Suppl 1: p. 929-30.
Evidenzklasse: Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=6 227884


25.Anderson, H. R., Pottier, A. C., and Strachan, D. P., Asthma from birth to age 23: incidence and relation to prior and concurrent atopic disease. Thorax, 1992. 47(7): p. 537-42.
Evidenzklasse: III
Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1412098


26.Arad, I. and Landau, H., Adrenocortical reserve of neonates born of long-term, steroid-treated mothers. Eur J Pediatr, 1984. 142(4): p. 279-80.
Evidenzklasse: IIa
Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=6092089


27.Arif, A. A., et al., Prevalence and risk factors of asthma and wheezing among US adults: an analysis of the NHANES III data. Eur Respir J, 2003. 21(5): p. 827-33.
Evidenzklasse: Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1 2765429


28.Arm, J. P., et al., The effects of dietary supplementation with fish oil lipids on the airways response to inhaled allergen in bronchial asthma. Am Rev Respir Dis, 1989. 139(6): p. 1395-400.
Evidenzklasse: III
Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2543246


29.Asher, M. I. and Weiland, S. K., The International Study of Asthma and Allergies in Childhood (ISAAC). ISAAC Steering Committee. Clin Exp Allergy, 1998. 28 Suppl 5: p. 52-66; discussion 90-1.
Evidenzklasse: III
Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9988448


30.Atherton, M., Outcome measures of efficiacy associated with a web-enabled asthma self-management programme: findings from a quasi-experiment. Dis Manag Health Outcomes, 2000. 8: p. 233-42.
Evidenzklasse: IIb
Link:


31.Austin, J. B., et al., Hay fever, eczema, and wheeze: a nationwide UK study (ISAAC, international study of asthma and allergies in childhood). Arch Dis Child, 1999. 81(3): p. 225-30.
Evidenzklasse: III
Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10451395


32.Ayres, J. G. and Campbell, L. M., A controlled assessment of an asthma self-management plan involving a budesonide dose regimen. OPTIONS Research Group. Eur Respir J, 1996. 9(5): p. 886-92.
Evidenzklasse: Ib
Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8793447


33.ÄZQ, Leitlinien-Clearingverfahren Asthma bronchiale. 2002.
Evidenzklasse: Link:
http://www.leitlinien.de/clearingverfahren/clearingberichte/asthma


34.ÄZQ and Qualitätssicherung, Ärztliche Zentralstelle für, Leitlinienbericht Asthma bronchiale. 2002.
Evidenzklasse: Link:
http://www.leitlinien.de/clearingverfahren/clearingberichte/asthma


35.Baena-Cagnani, C. E., et al., Comparative effects of desloratadine versus montelukast on asthma symptoms and use of beta 2-agonists in patients with seasonal allergic rhinitis and asthma. Int Arch Allergy Immunol, 2003. 130(4): p. 307-13.
Evidenzklasse: Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1 2740532


36.Bailey, W. C., et al., Asthma self-management: do patient education programs always have an impact? Arch Intern Med, 1999. 159(20): p. 2422-8.
Evidenzklasse: Ib
Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10665890


37.Baker, J., Am J Respir Crit Care Med, 1998. 157: A406.
Evidenzklasse: Link:


38.Barbato, A., et al., Asthma prevalence and drug prescription in asthmatic children. Allerg Immunol (Paris), 2003. 35(2): p. 47-51.
Evidenzklasse: Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1 2674038


39.Barbee, R. A. and Murphy, S., The natural history of asthma. J Allergy Clin Immunol, 1998. 102(4 Pt 2): p. S65-72.
Evidenzklasse: IV
Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9798724


40.Barnes, P. J., Poorly perceived asthma. Thorax, 1992. 47(6): p. 408-9.
Evidenzklasse: Link:


41.Barnes, P. J. and Pauwels, R. A., Theophylline in the management of asthma: time for reappraisal? Eur Respir J, 1994. 7(3): p. 579-91.
Evidenzklasse: IV
Link:


42.Barnett, P. L., et al., Intravenous versus oral corticosteroids in the management of acute asthma in children. Ann Emerg Med, 1997. 29(2): p. 212-7.
Evidenzklasse: Ib
Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9018184


43.Barr, R. G., et al., Sudden-onset asthma exacerbations: clinical features, response to therapy, and 2-week follow-up. Multicenter Airway Research Collaboration (MARC) investigators. Eur Respir J, 2000. 15(2): p. 266-73.
Evidenzklasse: III
Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10706490


44.Barritt, P. W. and Staples, E. B., Measuring success in asthma care: a repeat audit. Br J Gen Pract, 1991. 41(347): p. 232-6.
Evidenzklasse: III
Link:
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45.Bateman, J. R. and Clarke, S. W., Sudden death in asthma. Thorax, 1979. 34(1): p. 40-4.
Evidenzklasse: IV
Link:


46.Beamon, S., et al., Speleotherapy for asthma. Cochrane Database Syst Rev, 2001. 2.
Evidenzklasse: Link:
http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?db=m&form=6&dopt=r&uid=11406004


47.Beasley, R., Cushley, M., and Holgate, S. T., A self management plan in the treatment of adult asthma. Thorax, 1989. 44(3): p. 200-4.
Evidenzklasse: III
Link:


48.Becker, A. B., Nelson, N. A., and Simons, F. E., Inhaled salbutamol (albuterol) vs injected epinephrine in the treatment of acute asthma in children. J Pediatr, 1983. 102(3): p. 465-9.
Evidenzklasse: IIa
Link:


49.Becker, A. B. and Simons, F. E., Formoterol, a new long-acting selective beta 2-adrenergic receptor agonist: double-blind comparison with salbutamol and placebo in children with asthma. J Allergy Clin Immunol, 1989. 84(6 Pt 1): p. 891-5.
Evidenzklasse: Ib
Link:
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50.Becker, J. M., et al., Oral versus intravenous corticosteroids in children hospitalized with asthma. J Allergy Clin Immunol, 1999. 103(4): p. 586-90.
Evidenzklasse: Ib
Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10200005


51.Beilby, J. J., Wakefield, M. A., and Ruffin, R. E., Reported use of asthma management plans in South Australia. Med J Aust, 1997. 166(6): p. 298-301.
Evidenzklasse: III
Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9087186


52.Belamarich, P. F., et al., Do obese inner-city children with asthma have more symptoms than nonobese children with asthma? Pediatrics, 2000. 106(6): p. 1436-41.
Evidenzklasse: Link:
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53.Bentur, L., et al., Controlled trial of nebulized albuterol in children younger than 2 years of age with acute asthma. Pediatrics, 1992. 89(1): p. 133-7.
Evidenzklasse: Ib
Link:
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54.Berg, J., Dunbar-Jacob, J., and Sereika, S. M., An evaluation of a self-management program for adults with asthma. Clin Nurs Res, 1997. 6(3): p. 225-38.
Evidenzklasse: Ib
Link:
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55.Bernard-Bonnin, A. C., et al., Self-management teaching programs and morbidity of pediatric asthma: a meta-analysis. J Allergy Clin Immunol, 1995. 95(1 Pt 1): p. 34-41.
Evidenzklasse: Ia
Link:
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56.Beveridge, R. C., et al., Guidelines for the emergency management of asthma in adults. CAEP/CTS Asthma Advisory Committee. Canadian Association of Emergency Physicians and the Canadian Thoracic Society. Cmaj, 1996. 155(1): p. 25-37.
Evidenzklasse: nicht bewertet
Link:


57.Bhagat, R., et al., Rapid onset of tolerance to the bronchoprotective effect of salmeterol. Chest, 1995. 108(5): p. 1235-9.
Evidenzklasse: Ib
Link:


58.Bien, J. P., et al., Intravenous theophylline in pediatric status asthmaticus. A prospective, randomized, double-blind, placebo-controlled trial. Clin Pediatr (Phila), 1995. 34(9): p. 475-81.
Evidenzklasse: Ib
Link:


59.Blair, H., Natural history of childhood asthma. 20-year follow-up. Arch Dis Child, 1977. 52(8): p. 613-9.
Evidenzklasse: III
Link:
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60.Blumberg, M. Z., Morphine for severe asthma? N Engl J Med, 1973. 288(1): p. 50.
Evidenzklasse: Link:
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61.Blume and ZL-Expertentreffen., H (Hrsg.) 6., Bioäquivalenzbewertung
retardierter Theophyllin-Fertigarzneimittel. 1990, Frankfurt: Govi-Verlag,.
Evidenzklasse: Link:


62.Boldy, D. A. and Ayres, J. G., Nedocromil sodium and sodium cromoglycate in patients aged over 50 years with asthma. Respir Med, 1993. 87(7): p. 517-23.
Evidenzklasse: Ib
Link:
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63.Bosley, C. M., Fosbury, J. A., and Cochrane, G. M., The psychological factors associated with poor compliance with treatment in asthma. Eur Respir J, 1995. 8(6): p. 899-904.
Evidenzklasse: III
Link:
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64.Bosley, C. M., Parry, D. T., and Cochrane, G. M., Patient compliance with inhaled medication: does combining beta- agonists with corticosteroids improve compliance? Eur Respir J, 1994. 7(3): p. 504-9.
Evidenzklasse: Ib
Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8013609


65.Boulet, L. P., et al., Canadian Asthma Consensus Report, 1999. Canadian Asthma Consensus Group. Cmaj, 1999. 161(11 Suppl): p. S1-61.
Evidenzklasse: IV
Link:
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66.Boulet, L. P., et al., 1998 revision of the Canadian Asthma Consensus Guidelines. Asthma Consensus Conference Editorial Committee. Can Respir J, 1999. 6(3): p. 231-2.
Evidenzklasse: nicht bewertet
Link:
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67.Boulet, L. P., Turcotte, H., and Tennina, S., Comparative efficacy of salbutamol, ipratropium, and cromoglycate in the prevention of bronchospasm induced by exercise and hyperosmolar challenges. J Allergy Clin Immunol, 1989. 83(5): p. 882-7.
Evidenzklasse: Link:
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68.Braunstein, G. L., Trinquet, G., and Harper, A. E., Compliance with nedocromil sodium and a nedocromil sodium/salbutamol combination. Compliance Working Group. Eur Respir J, 1996. 9(5): p. 893-8.
Evidenzklasse: IIa
Link:
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69.Brenner, B. and Kohn, M. S., The acute asthmatic patient in the ED: to admit or discharge. Am J Emerg Med, 1998. 16(1): p. 69-75.
Evidenzklasse: IV
Link:
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70.British-Thoracic-Association, Death from asthma in two regions of England. BMJ, 1982. 285: p. 1251-5.
Evidenzklasse: Link:


71.British-Thoracic-Society, Guidelines for management of asthma in adults: II--Acute severe asthma. Statement by the British Thoracic Society, Research Unit of the Royal College of Physicians of London, King's Fund Centre, National Asthma Campaign. Bmj, 1990. 301(6755): p. 797-800.
Evidenzklasse: nicht bewertet
Link:


72.British-Thoracic-Society, Guidelines on the management of asthma. Statement by the British Thoracic Society, the Brit. Paediatric Association, the Research Unit of the Royal College of Physicians of London, the King's Fund Centre, the National Asthma Campaign, the Royal College of General Practitioners, the General Practitioners in Asthma Group, the Brit. Assoc. of Accident and Emergency Medicine, and the Brit. Paediatric Respiratory Group. Thorax, 1993. 48(2 Suppl): p. S1-24.
Evidenzklasse: nicht bewertet
Link:


73.British-Thoracic-Society, The British Guidelines on Asthma Management. Thorax, 1997. 52 Suppl 1: p. S1-21.
Evidenzklasse: nicht bewertet
Link:
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74.British-Thoracic-Society, Current best practice for nebuliser treatment. British Thoracic Society Nebulizer Project Groupx. Thorax, 1997. 52 Suppl 2: p. S1-3.
Evidenzklasse: nicht bewertet
Link:


75.British-Thoracic-Society, National Asthma Campaign, Royal College of Physicians of London in association
with the General Practitioners in Asthma Group, British Association of Accident and Emergency Medicine, British Paediatric Respiratory Society, Royal College of Paediatrics and Child Health.
The British guidelines on asthma management. 1995 review and position statement. Thorax, 1997. 52 (suppl 1): p. S1-S21.
Evidenzklasse: Link:


76.Britton, J., et al., Dietary magnesium, lung function, wheezing, and airway hyperreactivity in a random adult population sample. Lancet, 1994. 344(8919): p. 357-62.
Evidenzklasse: III
Link:
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77.Brocklebank, D., et al., Comparison of the effectiveness of inhaler devices in asthma and chronic obstructive airways disease: a systematic review of the literature. Health Technol Assess, 2001. 5(26): p. 1-149.
Evidenzklasse: Ia
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78.Brooke, A. M., et al., The natural history of respiratory symptoms in preschool children. Am J Respir Crit Care Med, 1995. 152(6 Pt 1): p. 1872-8.
Evidenzklasse: III
Link:
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79.Brooks, L. J., Cloutier, M. M., and Afshani, E., Significance of roentgenographic abnormalities in children hospitalized for asthma. Chest, 1982. 82(3): p. 315-8.
Evidenzklasse: III
Link:


80.Brophy, C., et al., How long should Atrovent be given in acute asthma? Thorax, 1998. 53(5): p. 363-7.
Evidenzklasse: Ib
Link:
http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/referer?http://www.thoraxjnl.com/cgi/content/full/53/5/363


81.Browne, G. J., et al., Randomised trial of intravenous salbutamol in early management of acute severe asthma in children. Lancet, 1997. 349(9048): p. 301-5.
Evidenzklasse: Ib
Link:


82.Bryant, D. H., Nebulized ipratropium bromide in the treatment of acute asthma. Chest, 1985. 88(1): p. 24-9.
Evidenzklasse: Ib
Link:


83.Bryce, F. P., et al., Controlled trial of an audit facilitator in diagnosis and treatment of childhood asthma in general practice. Bmj, 1995. 310(6983): p. 838-42.
Evidenzklasse: Ib
Link:
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84.Bucknall, C. E., et al., Scottish Confidential Inquiry into Asthma Deaths (SCIAD), 1994-6. Thorax, 1999. 54(11): p. 978-84.
Evidenzklasse: III
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85.Bundgaard, A., Rasmussen, F. V., and Madsen, L., Pretreatment of exercise-induced asthma in adults with aerosols and pulverized tablets. Allergy, 1980. 35(8): p. 639-45.
Evidenzklasse: Link:
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86.Burr, M. L., et al., A confidential inquiry into asthma deaths in Wales. Thorax, 1999. 54(11): p. 985-9.
Evidenzklasse: III
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87.Burr, M. L., Verrall, C., and Kaur, B., Social deprivation and asthma. Respir Med, 1997. 91(10): p. 603-8.
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542.SIGN and 2002, Pharmacological management of asthma. Evidence table 4.4c: inhaled corticosteroid vs leukotriene receptor antagonists. SIGN; 2002, 2002.
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543.SIGN and 2002, Pharmacological management of asthma. Evidence table 4.4j: do cromones work as first line preventor in children >5 years? SIGN, 2002. Edinburgh: SIGN, 2002., 2002.
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544.SIGN and 2002, Pharmacological management of asthma. Evidence table 4.21: Aspirin intolerant asthma. SIGN; 2002, 2002.
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545.SIGN and Network, Scottish Intercollegiate Guidelines, Primary Care Management of Asthma. SIGN Publication No. 33, 1998.
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547.SIGN and Scottish Intercollegiate Guidelines Network , The British Thoracic Society, British Guideline on the Management of Asthma. Evidence table 4.13a: Immunosuppresive agents. Thorax, 2003. 58: p. Suppl.1.
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563.Spitzer, W. O., et al., The use of beta-agonists and the risk of death and near death from asthma. N Engl J Med, 1992. 326(8): p. 501-6.
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